Scientist Peptide Chemistry

Who We Are

At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs.

What We Do

Neurocrine Biosciences is a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The companys diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntingtons disease, classic congenital adrenal hyperplasia, endometriosis* and uterine fibroids,* as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedIn, X and Facebook. (*in collaboration with AbbVie)

About The Role

Supports the design, synthesis and characterization of novel peptides to discover next-generation peptide-based therapeutics. Applies synthetic working knowledge and design and synthetic skills to enable progress in peptide-related drug discovery.

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Your Contributions (include, But Are Not Limited To)

• Supports the synthesis, purification and characterization of peptides, small proteins and chemically-modified analogs using state-of-the-art synthesis, purification, analytical and biophysical techniques
• Participate in projects and teams towards agreed-upon goals, ultimately working towards candidate peptide nomination
• Independent data-driven optimization of peptide SAR
• Aid in lab setup, instrument purchase, installation and ongoing lab operations
• Effective communication of scientific rationale, results and interpretation at project, team and departmental meetings, contributing to strategic discussions
• Active collaboration and sharing of expertise with colleagues
• Performs other job-related duties as assigned
  
  

Requirements

• BS/BA degree in chemistry or closely related field and 2+ years experience in peptide synthesis, purification, and characterization, with complex synthetic strategies and modern peptide chemistry techniques OR
• MS/MA degree in chemistry or closely related field and some similar experience as noted above OR
• PhD or equivalent in chemistry or closely related field preferred and some similar experience as noted above
• Working on proficiency in all aspects of modern peptide synthesis, purification and analysis; capable of immediate independent laboratory work on solid- and solution-phase chemistry
• Strong understanding of peptide structure and associated biophysical techniques to assess peptide structure, stability and behavior in solution
• Demonstrated knowledge with bioconjugation and time-extension strategies for peptides
• Strong interpersonal skills with strong oral and written communication abilities
• Assimilates data and research findings outside of Neurocrine for application to new scientific projects
• Good track record in peptide technologies and hit discovery
  
  

Neurocrine Biosciences is an EEO/Disability/Vets employer.

We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description.

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The annual base salary we reasonably expect to pay is $89,800.00-$123,000.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 20% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.

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